July 2, 2026 – James Roza, VP of Technical Services at Biovivo Science, says that formulators are developing products that take a more comprehensive approach to conditions that can lead to cognitive impairment, as they recognize the interconnectedness of different health areas.
“As we advance technologically, many consumers struggle with the ability to cope with the greater demands being placed on their brains. Retaining information, maintaining focus, and multitasking become increasingly difficult as a result, adding stress and reducing the quality of sleep.”
Meanwhile, he also highlights several challenges in formulating a cognitive enhancement product: bioavailability, the ability to cross the blood-brain barrier, and targeting the right metabolic pathway that produces acetylcholine, dopamine, or other neurotransmitters.
“All of these should be given thoughtful consideration and backed by scientific evidence. Crossing the protective layer of the brain for entry is critical for its ability to modulate neural pathways and operate at a cellular level,” says Roza.
Boswell at Kerry adds that demonstrating real efficacy is challenging as well, since improvements in cognition may be subtle or gradual, often requiring robust clinical studies over time.
“Large trials are costly and sometimes yield mixed results, so companies must invest in strong science to back up their claims and meet regulatory standards for cognitive health benefits.”
Moreover, Boswell highlights that many natural brain-boosting ingredients pose formulation challenges due to their bitter flavors, stability issues, or limited bioavailability. He says that consumer expectations on taste and sensory experience also continue to rise, going beyond flavor to include mouthfeel and aftertaste.
“Innovators are overcoming these hurdles with advanced delivery technologies and functional food formats, ensuring consumers get effective doses in convenient, enjoyable forms.”
___
Originally Published in
Nutrition Insight
Date
July 2, 2026
Read the full article
https://www.nutritioninsight.com/special-reports/brain-health-supplements-cognitive-performance.html

